Autoimmune problems often produce a patchwork of symptoms: fatigue, joint or muscle pain, skin rashes, digestive issues, low-grade fevers, or sensitivity to cold and heat.

Symptoms may flare and then subside, affecting multiple systems of the body and sometimes shifting over time, which can make diagnosis difficult and frustrating.

Some examples of autoimmune conditions include Hashimoto’s Thyroiditis, Rheumatoid Arthritis, Crohns Disease, Ulcerative Colitis, Lupus (SLE) Psoriasis.

Widespread pain affecting muscles, joints, or connective tissue, often described as aching, burning, or stabbing. Pain can move around the body and worsen with stress, poor sleep, or weather changes.

Tender points, stiffness, restless legs, headaches, gut issues, and overwhelming fatigue frequently occur alongside the pain, making daily life unpredictable.

Constant exhaustion that doesn’t improve with rest. Brain fog, poor concentration, headaches, dizziness, or feeling “wired but tired” at night are common.

Symptoms can persist for months or years, even when routine medical tests show no abnormalities.

Recurring bloating, abdominal pain, reflux, constipation, diarrhoea, or alternating bowel habits. Some notice food triggers, nausea, or early fullness after eating.

These symptoms may come and go in cycles, interfere with daily activities, and are often labelled as “IBS” especially when multiple tests have been done and no obvious cause is found.

Clusters of vague or shifting symptoms that don’t fit neatly into one diagnosis. These can include dizziness, palpitations, numbness or tingling, headaches, blurred vision, temperature intolerance, or flu-like symptoms.

Such symptoms may come and go, change location, or fluctuate in severity, often leaving people feeling dismissed or misunderstood.

Irregular, heavy or painful menstrual cycles, hot flushes and night sweats, acne, hair loss, unwanted hair growth, mood swings, low libido, or fertility struggles.

For some, symptoms are linked to PCOS, endometriosis, menopause, thyroid changes, or low testosterone.

These imbalances often affect energy, metabolism, weight, and emotional wellbeing.

Difficulty falling asleep, waking frequently, or feeling unrefreshed even after a full night in bed.

Insomnia, nightmares, restless legs, choking in your sleep or excessive snoring may be present. Poor sleep often leads to daytime fatigue, poor concentration, low mood, and worsening of other symptoms such as pain or digestive upset.

Difficulty losing or maintaining weight despite repeated efforts with diet and exercise. Weight changes may occur alongside fatigue, low mood, disrupted sleep, cravings, or hormonal fluctuations (such as irregular periods, thyroid changes, or blood sugar problems).

Many people describe feeling as though their body is “working against them.”

Uncertainty when a diagnosis feels incomplete, contradictory, or doesn’t explain ongoing symptoms.

Some have been told “nothing more can be done,” while others feel misdiagnosed or brushed aside.

Seeking a second opinion is common for those still searching for clarity, reassurance, or a broader explanation of what’s happening.